Redox and metabolic regulation of transcription
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چکیده
منابع مشابه
Redox and metabolic regulation of transcription
Reactive oxygen species (ROS) production and the resultant shift in the cellular redox state can exert a biphasic effect on cellular functions such as survival, migration or proliferation. At high levels, ROS can induce broad DNA and protein damage which can result in cell death, but at lower levels ROS act as signaling molecules that sustain proliferation or activate specific stress-response p...
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Reactive oxygen species (ROS) are implicated in the pathogenesis of a wide variety of human diseases. Recent evidence suggests that at moderately high concentrations, certain forms of ROS such as H202 may act as signal transduction messengers. To develop a better understanding of the exact mechanisms that underlie ROS-dependent disorders in biological systems, recent studies have investigated t...
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From the Department of Plant Physiology and Umeå Plant Science Centre, Umeå University, SE-901 87 Umeå, Sweden Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, SLU, SE-901 87 Umeå, Sweden Biochemistry and Physiology of Plants, Faculty of Biology, W5, Bielefeld University, 33501 Bielefeld, Germany Department of Chemistry, Center of Chemical Biology and Computational...
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Transcription factors of the forkhead box, class O (FoxO) family are important regulators of the cellular stress response and promote the cellular antioxidant defense. On one hand, FoxOs stimulate the transcription of genes coding for antioxidant proteins located in different subcellular compartments, such as in mitochondria (i.e. superoxide dismutase-2, peroxiredoxins 3 and 5) and peroxisomes ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.13459